Clinical Edge Journal Scan

Active disease in third trimester increases risk for emergency caesarean section in PsA


 

Key clinical point: Women with psoriatic arthritis (PsA) were at an increased risk for emergency caesarean section, with active disease in the third trimester further amplifying the risk, highlighting the importance of pregestational counseling and disease control along with systematic monitoring during pregnancy.

Major finding: Compared with control individuals, women with PsA had a higher risk for caesarean section (risk difference [RD] 15.0%; P < .001) and for emergency caesarean section (RD 10.6%; P < .001), with active disease in the third trimester further amplifying both risks (caesarean section: RD 17.7%; P = .028; emergency caesarean section: RD 15.9%; P = .015).

Study details: The data come from a population-based cohort study that included women with PsA (n = 121), women with axial spondyloarthritis (n = 312), and control individuals (n = 575,798) with singleton births.

Disclosures: This study was funded by The Norwegian Women’s Public Health Association. The authors did not declare any conflicts of interest.

Source: Skorpen CG et al. Caesarean section in women with axial spondyloarthritis and psoriatic arthritis: A population-based study. RMD Open . 2023;9(1):e002760 (Mar 2). Doi: 10.1136/rmdopen-2022-002760

Recommended Reading

Real-world evidence on impact of PsA manifestation on patient outcomes
Psoriatic Arthritis ICYMI
Crude mortality rate doubled in PsA patients during COVID-19 pandemic
Psoriatic Arthritis ICYMI
Circulating microRNA can differentiate between psoriasis and psoriatic arthritis
Psoriatic Arthritis ICYMI
Baseline cardiovascular risk may influence MACE and malignancy incidences in tofacitinib-treated PsA patients
Psoriatic Arthritis ICYMI
Long-term safety and tolerability of upadacitinib in PsA
Psoriatic Arthritis ICYMI
PsA: Baseline disease activity predicts DAPSA response in patients treated with apremilast
Psoriatic Arthritis ICYMI
Commentary: Concerning PsA treatments and comorbidities, March 2023
Psoriatic Arthritis ICYMI
Psoriatic arthritis treatment for women falls short, study suggests
Psoriatic Arthritis ICYMI
Gender-based differences in treatment outcomes and persistence with ustekinumab or TNFi in PsA
Psoriatic Arthritis ICYMI
Achievement of low disease activity improves long-term structural damage in PsA
Psoriatic Arthritis ICYMI