Repeated reduced diphtheria toxoid and acellular pertussis (Tdap) vaccination has acceptable safety relative to Tdap vaccination followed by tetanus toxoid, reduced diphtheria (Td) vaccination, according to a recent study. In light of waning immunity to pertussis following receipt of Tdap vaccine, maintaining protection may require repeated Tdap vaccination. Researchers evaluated the safety of repeated doses of tetanus‐containing vaccine in 68,915 non-pregnant adolescents and adults in the Vaccine Safety Datalink population who had received an initial dose of Tdap. They found that compared with 7,521 subjects who received a subsequent dose of Td vaccine, the 61,394 subjects who received a subsequent dose of Tdap did not have significantly elevated risk of medical visits for seizure, cranial nerve disorders, limb swelling, pain in limb, cellulitis, paralytic syndromes, or encephalopathy/encephalitis/meningitis.