Clinical Edge

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Aiming for Earlier Cerebral Palsy Diagnosis

JAMA Pediatr; ePub 2017 Jul 17; Novak, et al

Although the diagnosis of cerebral palsy (CP) is typically made between 12 and 24 months of age, there is evidence to indicate it can be detected before 5 months’ corrected age, according to a systematic review of the medical literature. Among the findings:

  • Before 5 months’ corrected age, there are several tests that can accurately predict the presence of CP, including MRI, which has a sensitivity rating of 86%-89%.
  • The Prechtl Qualitative Assessment of General Movements and the Hammersmith Infant Neurological Examination are also valuable, with sensitivities of 98% and 90%,respectively.
  • Early diagnosis is being encouraged because the sooner the disease is discovered, the faster treatments that optimize function and neuroplasticity can be implemented.

Citation:

Novak I, Morgan C, Adde L, et al. Early, accurate diagnosis and early intervention in cerebral palsy advances in diagnosis and treatment. [Published online ahead of print July 17, 2017]. JAMA Pediatr. doi:10.1001/jamapediatrics.2017.1689.