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Accuracy of Urinalysis in Young Febrile Infants

Pediatrics; ePub 2018 Feb 1; Tzimenatos, et al

Although some experts have questioned the accuracy of urinalysis for diagnosing urinary tract infection (UTI) in young febrile infants, a recent data analysis concluded that it is, in fact, a sensitive and specific way to detect the infection. The analysis included >4,000 infants, ≤60 days old, who were seen in 26 emergency departments. Researchers found:

  • 289 patients (7%) had UTIs with colony counts of ≥50,000 CFUs/mL, which included 27 (9.3%) who also had bacteremia.
  • A positive urinalysis had a 94% sensitivity rate, which climbed to 100% when bacteremia was factored in.
  • Specificity was 91% in all groups.
  • Specificity and sensitivity ratings were better in febrile infants when colony counts were ≥50,000.

Citation:

Tzimenatos L, Mahajan P, Dayan PS, et al. Accuracy of the urinalysis for urinary tract Infections in febrile infants 60 days and younger. [Published online ahead of print February 1, 2018]. Pediatrics. doi:10.1542/peds.2017-3068.