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Prenatal Perfluorooctanoic Acid Exposure and Onset AD

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Children with a higher prenatal perfluorooctanoic acid (PFOA) exposure have a higher risk of earlier atopic dermatitis (AD) development, a new study found. In a 5-year follow-up study, researchers sought to investigate the association between prenatal perfluoroalkyl substance (PFAS) exposure and earlier onset of AD in children. PFAS levels were analyzed from cord blood. Among the details:

  • 863 mother-infant pairs, including children aged 0-5 years with AD, were included.
  • The prevalence of physician-diagnosed AD before age 5 years was 7.1%.
  • Cord blood PFAS was associated with significantly increased AD risk.
  • Prenatal PFOA exposure was associated with earlier onset of AD in children.

Citation:

Wen HJ, Wang SL, Chuang YC, Chen PC, Guo YL. Prenatal perfluorooctanoic acid exposure is associated with early onset atopic dermatitis in 5-year-old children. [Published online ahead of print May 16,2019]. Chemosphere. doi: 10.1016/j.chemosphere.2019.05.100.

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