In women with hypertensive disorders of pregnancy, nonsteroidal anti-inflammatory drug (NSAID) drug administration is not associated with increased blood pressure (BP), a recent study found. Researchers conducted a retrospective cohort study in which patients were analyzed in 2 groups according to whether they received NSAIDs postpartum. The primary outcome was change in mean arterial pressure during the postpartum period. They found:

• 276 women with hypertensive disorders of pregnancy were included (129 NSAID-unexposed and 147 NSAID-exposed).
• Postpartum NSAID administration was not associated with a statistically significant change in mean arterial pressure vs no NSAID administration.
• No difference was observed between the cohorts in terms of need for initiation or increase in dose of antihypertensive agents or maternal readmission for hypertensive disorder.