Nausea and vomiting during pregnancy is associated with a lower risk of pregnancy loss in pregnant women, a recent study found. The secondary analysis of the Effects of Aspirin in Gestation and Reproduction enrolled women with 1 or 2 prior pregnancy losses at 4 US clinical centers from June 15, 2007, to July 15, 2011, and was limited to women with a pregnancy confirmed by positive results of a human chorionic gonadotropin (hCG) test. Nausea symptoms were ascertained from daily preconception and pregnancy diaries for gestational weeks 2 to 8. Researchers found:

• A total of 797 women (mean age, 28.7 years) had an hCG-confirmed pregnancy.
• 188 (23.6%) pregnancies ended in loss.
• 73 of 409 (17.8%) women reported nausea without vomiting at gestational week 2, and 11 of 409 (2.7%) women nausea with vomiting.
• By week 8, proportions increased to 254 of 442 (57.3%) women and 118 of 443 (26.6%) women, respectively.
• Hazard ratios (HRs) for nausea (0.50) and nausea with vomiting (0.25) were inversely associated with pregnancy loss.
• Nausea (HR, 0.44) and nausea with vomiting (HR, 0.20) were associated with a reduced risk for clinical pregnancy loss.