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Vitamin D Level’s Impact on Attaining Response
Clin Breast Cancer; ePub 2017 Dec 11; Chiba, et al
Low vitamin D levels in women with breast cancer was linked with a failure to attain pathologic complete response in a study involving 144 individuals. Participants included American and French women who had their vitamin D level measured before or during neoadjuvant chemotherapy. Investigators looked at vitamin D deficiency and pathologic complete response. Among the results:
- Average BMI in US women was 28.8, vs 24.8 in the French cohort.
- Average vitamin D levels were 27.5 and 21.5 ng/mL, respectively.
- After adjusting for certain variables, patients with vitamin D deficiency were more than twice as likely to not attain pathologic complete response.
Citation:
Chiba A, Raman R, Lamy P, et al. Serum vitamin D levels impacts pathologic complete response in patients undergoing neoadjuvant systemic therapy for operable breast cancer. [Published online ahead of print December 11, 2017]. Clin Breast Cancer. doi:10.1016/j.clbc.2017.12.001.