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Low-Fat Diet Did Not Improve Brain MRIs in MS

Mult Scler Relat Disord; ePub 2016 Jul 6; Yadav, et al

Publish date:: July 19, 2016

While a very low-fat, plant-based diet was well adhered to and tolerated, it resulted in no significant improvement on brain MRI, relapse rate, or disability as assessed by the Expanded Disability Status Scale (EDSS) scores in subjects with relapsing-remitting multiple sclerosis, according to a recent study. Researchers conducted a randomized-controlled, 1-year-long study with 61 participants assigned to either diet (n=32) or wait-listed (control, n=29) group. They found:

• The 2 groups showed no differences in brain MRI outcomes, number of MS relapses, or disability at 12 months.

• The diet group showed improvements at 6 months in low-density lipoprotein cholesterol, total cholesterol and insulin, mean monthly reductions in BMI, and fatigue during the 12-month period.

Citation: Yadav Y, Marracci G, Kim E, et al. Low-fat, plant-based diet in multiple sclerosis: A randomized controlled trial. [Published online ahead of print July 6, 2016]. Mult Scler Relat Disord. doi:10.106./j.msard.2016.07.001.

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