An epilepsy admission was independently associated with subsequent hospital readmission for psychotic episodes, even after adjustment for confounding variables, a recent study found. There were 58,278 index admissions for epilepsy, and researchers compared this group against admissions for stroke (n=215,821) and common medical causes (pneumonia, urinary tract infection [UTI], congestive heart failure [CHF], and chronic obstructive pulmonary disease [COPD], n=973,078). Readmission rates for psychotic episodes within 90 days from discharge for index hospitalizations were calculated. They found:

• Up to 90 days from index admission, there were 683/100,000 readmissions for psychotic episodes in the epilepsy group, 92/100,000 in the stroke group, and 58‐206/100,000 in the medical group.
• The relative rate of readmission in the epilepsy group was highest in the first 30 days following index admission (311/100,000).
• Unadjusted hazard ratio (HR) for readmission for psychotic episodes within 1 year in the epilepsy group compared to the stroke group was 6.58 and 4.41, compared to the medical group.
• Confounding factors most strongly associated with psychosis readmission were documented psychosis history at the time of index admission, younger age, and lower income quartile.