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Refractory RA responds to vagus nerve stimulation

Publish date:: June 25, 2019

Key clinical point: Vagus nerve stimulation is an investigational approach showing promise in refractory RA.

Major finding: Five out of 10 patients showed improvements in disease activity; two achieved remission.

Study details: A 12-week, “first in-human” pilot study of an investigational, surgically implanted neurostimulator in 14 patients with refractory RA.

Disclosures: The study was sponsored by SetPoint Medical. Dr. Genovese disclosed receiving consulting fees from and having contracts with/grants with SetPoint and acting as a consultant to Galvani and Vorso. He has also received research support from and served as a consultant to Sanofi/Genzyme, Genentech/Roche, and R-Pharm.

Citation:

Genovese M et al. Ann Rheum Dis. Jun 2019; 78(Suppl 2):264. Abstract LB0009, doi: 10.1136/annrheumdis-2019-eular.8716

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