Clinical Edge

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Methotrexate Does Not Cause Rheumatoid Interstitial Lung Disease

Key clinical point: There is no association between incident interstitial lung disease (ILD) and methotrexate treatment in patients with RA.

Major finding: Methotrexate exposure was not associated with incident RA-ILD (odds ratio, 0.85; P = .578).

Study details: Two prospective, multicenter early RA inception cohorts involving 2,701 patients.

Disclosures: The study had no specific outside funding. The reporting investigator reported having no conflicts of interest.

Citation:

Kiely P et al. Rheumatology. 2019;58(suppl 3), Abstract 009.