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Study explores reasons for link between gastroparesis symptoms, constipation

Publish date:: November 10, 2020

Key clinical point: Constipation commonly affects patients with symptoms of gastroparesis and shows a significant positive correlation with symptom severity.

Major finding: In all, 34% of patients with gastroparesis symptoms had severe constipation. In the multivariable analysis, severe constipation (a score of 4 or 5 on a 5-point scale) correlated significantly with a higher score on the Gastroparesis Cardinal Symptoms Index (GCSI), with an odds ratio of 1.85 (95% confidence interval, 1.30-2.67).

Study details: Prospective study of 338 patients.

Disclosures: The National Institute of Diabetes and Digestive and Kidney Diseases provided funding. The investigators reported having no conflicts of interest.

Citation:

Source: Parkman HP et al. Clin Gastroenterol Hepatol. 2020 Oct 28. doi: 10.1016/j.cgh.2020.10.045.

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