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ACP Guidance on Pharmacologic Treatment of T2D
Ann Intern Med; ePub 2018 Mar 6; Qaseem, et al
Clinicians should personalize goals for glycemic control in patients with type 2 diabetes (T2D), according to new guidance released by The American College of Physicians (ACP). The guidance statement was developed to guide clinicians in selecting hemoglobin A1c targets with pharmacologic therapy for nonpregnant adults with type 2 diabetes (T2D). Guidance statements include:
- Clinicians should personalize goals for glycemic control in patients with T2D on the basis of a discussion of benefits and harms of pharmacotherapy, patients' preferences, patients' general health and life expectancy, treatment burden, and costs of care.
- Clinicians should aim to achieve an HbA1c level between 7% and 8% in most patients with T2D.
- Clinicians should consider deintensifying pharmacologic therapy in patients with T2D who achieve HbA1c levels <6.5%.
- Clinicians should treat patients with T2D to minimize symptoms related to hyperglycemia and avoid targeting an HbA1c level in patients with a life expectancy <10 years due to advanced age (≥80 years), residence in a nursing home, or chronic conditions (such as dementia, cancer, end-stage kidney disease, or severe chronic obstructive pulmonary disease or congestive heart failure) because the harms outweigh the benefits in this population.
Qaseem A, Wilt TJ, Kansagara D, et al. Hemoglobin A1c targets for glycemic control with pharmacologic therapy for nonpregnant adults with type 2 diabetes mellitus: A guidance statement update from the American College of Physicians. [Published online ahead of print March 6, 2018]. Ann Intern Med. doi:10.7326/M17-0939.
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