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Can Antimicrobial PICCs Reduce CLABSI Risk?
Am J Infect Control; ePub 2016 Oct 27; Kramer, et al
Antimicrobial peripherally inserted central catheters (PICCs) may reduce central line-associated bloodstream infection (CLABSI), especially in high-risk subgroups, a recent study found. This study of 12,879 adult and pediatric patients from intensive care, long-term care, and general ward settings evaluated whether antimicrobial PICCs are associated with CLABSI reduction. Researchers found:
- Incidence of CLABSI in patients with antimicrobial PICCs was 0.2% and incidence among nonantimicrobial catheters was 5.3%.
- Antimicrobial PICCs were associated with a significant reduction in CLABSI (RR, 0.29) when compared with noncoated PICCs.
- 26 patients needed to be treated with antimicrobial PICCs to prevent 1 CLABSI.
- Adults at greater baseline risk of CLABSI had greater reduction in CLABSI (RR, 0.20).
Kramer RD, Rogers MA, Conte M, Mann J, Saint S, Chopra V. Are antimicrobial peripherally inserted central catheters associated with reduction in central line-associated bloodstream infection? A systematic review and meta-analysis. [Published online ahead of print October 27, 2016]. Am J Infect Control. doi:10.1016/j.ajic.2016.07.021.