Leukemia, Myelodysplasia, Transplantation
News
Targeting enzymes to treat leukemias
Credit: Volker Brinkmann Enzymes linked to diabetes and obesity appear to play key roles in arthritis and leukemia, according to research...
News
Cord blood product gets orphan designation
Credit: NHS The US Food and Drug Administration (FDA) has granted orphan designation to a cord blood product called NiCord for the treatment of...
Conference Coverage
Maintenance prolongs PFS, not OS, in relapsed CLL
Credit: Linda Bartlett SAN FRANCISCO—Maintenance therapy with the anti-CD20 monoclonal antibody ofatumumab improves progression-free survival (PFS...
News
Ibrutinib proves active in high-risk CLL
Credit: Mary Ann Thompson Single-agent ibrutinib can elicit a high response rate in patients with high-risk chronic lymphocytic leukemia (CLL),...
Conference Coverage
Anti-CD38 antibodies poised to transform myeloma treatment
Key clinical point: The investigational anti-CD38 antibodies SAR650984 and daratumumab in combination with standard regimens were highly active in...
News
Certain cancers primarily result from ‘bad luck’
in the bone marrow Scientists have created a statistical model that measures the proportion of cancer incidence, across many tissue types, caused...
Conference Coverage
CARs come in different makes and models
Credit: NIAID SAN FRANCISCO—CTL019, a chimeric antigen receptor (CAR) T cell targeting CD19, is not the only CAR in the production line....
Conference Coverage
CAR is feasible in majority of ALL patients, team says
Credit: Bill Branson SAN FRANCISCO—A chimeric antigen receptor (CAR) T-cell therapy is feasible in 90% of heavily pretreated or transplanted...
Conference Coverage
CAR produces durable responses in B-cell ALL
Credit: Charles Haymond SAN FRANCISCO—JCAR015, a chimeric antigen receptor (CAR) T-cell therapy, can produce durable responses in patients with B...
News
New data added to obinutuzumab label
Credit: Bill Branson The US Food and Drug Administration (FDA) has approved a supplemental biologics license application for obinutuzumab (Gazyva...
News
Study shows higher risk of MDS, leukemia after breast cancer
chemotherapy Credit: Rhoda Baer The risk of developing myelodysplastic syndromes (MDS) or leukemias after treatment for early stage breast cancer...