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Ultraviolet Radiation and Hodgkin Lymphoma

Assessing the association

Publish date:: February 24, 2016

There is an inverse association between ultraviolet radiation (UVR) and Hodgkin lymphoma (HL), according to a study of 20,021 patients with HL listed in 15 population-based US cancer registries. Ground-based ambient UVR estimates were linked to county of diagnosis. Researchers calculated Hodgkin lymphoma incidence rate ratios (IRRs) for these HL subtypes:

Nodular sclerosis (IRR=0.84).
Mixed cellularity/lymphocyte-depleted (IRR=0.66).
Lymphocyte-rich (IRR=0.71).
Nodular lymphocyte predominant HL (IRR=0.74).
“Not otherwise specified” HL (IRR=1.19)

Citation: Bowen EM, Pfeiffer RM, Linet MS, et al. Relationship between ambient ultraviolet radiation and Hodgkin lymphoma subtypes in the United States. [Published online ahead of print February 18, 2016]. Br J Cancer. doi:10.1038/bjc.2015.383.

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