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Pregnancy in Hodgkin Lymphoma

Assessing risk of relapse

Publish date:: December 23, 2015

Pregnancy after diagnosis does not increase the relapse rate among women whose Hodgkin lymphoma (HL) is in remission, according to a study of 449 women with HL, including 144 who became pregnant during follow-up. Researchers found:

• Overall, 47 relapses were recorded, 1 of which was pregnancy-associated.

• Adjusted hazard ratio comparing pregnancy-associated relapse rate vs non-pregnancy relapse rate was 0.29.

• The expected number of relapses in women with a recent pregnancy was 3.76; the observed-to-expected ratio was 0.27.

Citation: Weibull CE, Eloranta S, Smedby KE, et al. Pregnancy and the risk of relapse in patients diagnosed with Hodgkin lymphoma. [Published online ahead of print December 14, 2015]. J Clin Oncol. doi:10.1200/JCO.2015.63.3446.

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