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Despite Advances, CMML Survival Odds Remain Poor

Leuk Lymphoma; ePub 2016 Nov 23; Guru Murthy, et al

People with chronic myelomonocytic leukemia (CMML) have very poor odds of survival, despite advances in biology and therapy, according to a study involving more than 2,200 individuals.

Investigators looked at participants who had CMML that was diagnosed over an 11-year period ending in 2013. Among the results:

  • Incidence was significantly higher with advancing age.
  • It was lower in females, blacks, and Asians/Pacific Islanders.
  • Patients 20-39 years of age survived a median of 25 months; those aged 40-59, 20 months; 60 to 79, 18 months; 80 and older, 11 months.
  • Overall survival during 2007–2013 was 17 months, vs 14 months during 2003–2006.

Citation:

Guru Murthy G, Dhakal I, Mehta P. Incidence and survival outcomes of chronic myelomonocytic leukemia in the United States. [Published online ahead of print November 23, 2016]. Leuk Lymphoma. doi:10.1080/10428194.2016.1258700.