Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

SRA737 + Anti–PD-L1 Therapy and Low-Dose Gemcitabine Shows Promise for SCLC

Key clinical point: SRA737 with anti–PD-L1 therapy and low-dose gemcitabine led to tumor regression in a preclinical small cell lung cancer (SCLC) model.

Major finding: The triple combination led to tumor regression as early as 14 days, with CRs in 8 of 10 cases.

Study details: A preclinical mouse model study.

Disclosures: Dr. Sen reported having no disclosures.

Citation:

Sen T et al. AACR 2019, Abstract LB-148.