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Rates of EBV-Positive DLBCL Higher in Jordan, Turkey
Key clinical point: A retrospective study suggests the prevalence of Epstein Barr virus–positive (EBV+) diffuse large B-cell lymphoma (DLBCL) is higher in Jordan and Turkey, compared with western countries.
Major finding: After in situ hybridization analysis, 10% of Jordanian patients and 12% Turkish patients were positive for EBV-encoded RNA 1. Other studies have shown an incidence of 0%-4% in the United States.
Study details: A retrospective case series of 100 patients with DLBCL. Fifty cases were from patients in Jordan and 50 cases were from patients in Turkey.
Disclosures: No funding sources were reported. The authors reported having no conflicts of interest.
Aladily TN et al. Ann Diagn Pathol. 2019 Sep 3. doi: 10.1016/j.anndiagpath.2019.151406.