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MATRIX-RICE Plus Transplant Looks Effective in Poor Prognosis DLBCL Group

Key clinical point: The combination of MATRIX-RICE chemotherapy plus autologous transplant appears effective in patients with diffuse large B-cell lymphoma and secondary central nervous system (CNS) dissemination.

Major finding: At 1 year, the trial met a pre-specified threshold for progression-free survival.

Study details: A phase 2 trial enrolling 79 patients with diffuse large B-cell lymphoma and CNS involvement.

Disclosures: Dr. Ferreri reported disclosures related to Celgene, Gilead, Novartis, and Roche.

Citation:

Ferreri AJM et al. ASH 2019, Abstract 353.