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Risk of Atrial Fibrillation in Patients with CLL

Leuk Lymphoma; ePub 2016 Nov 25; Shanafelt, et al

A model can predict atrial fibrillation risk in people with chronic lymphocytic leukemia (CLL), according to a study involving more than 2,400 individuals.

Investigators looked at atrial fibrillation at CLL diagnosis, as well as risk of developing it later. Among the results:

  • 6% of patients had atrial fibrillation at CLL diagnosis.
  • Among the ~2,300 without a history of atrial fibrillation, 6% developed it during follow-up—an incidence rate of ~1%/year.
  • Older age, male gender, valvular heart disease, and hypertension were linked with risk of developing atrial fibrillation.

Citation:

Shanafelt T, Parikh S, Noseworthy P, et al. Atrial fibrillation in patients with chronic lymphocytic leukemia. [Published online ahead of print November 25, 2016]. Leuk Lymphoma. doi:10.1080/10428194.2016.1257795.