Clinical Edge Journal Scan

Advanced gastric cancer: Surgical palliation worsens survival outcomes


 

Key clinical point: In patients with advanced gastric cancer, surgical vs nonsurgical palliation is associated with a significantly shorter overall survival (OS) and a significantly higher hazard of mortality.

Major finding: The use of surgical palliation declined significantly during 2004-2015 ( P < .0001). The median OS was significantly longer in patients who received nonsurgical vs surgical palliation (6.0 vs 3.6 months; P < .001). Surgical vs nonsurgical palliation was associated with a significantly higher risk for mortality (adjusted hazard ratio 1.20; P < .001).

Study details: A retrospective study of 6829 patients with clinical stage IV gastric cancer from the National Cancer Database (2004-2015) who received surgical or nonsurgical palliation.

Disclosures: This study did not receive any funding. The authors declared no conflicts of interest.

Source: Nohria A et al. Outcomes after surgical palliation of patients with gastric cancer. J Surg Res. 2022;279:304-311 (Jul 6). Doi: 10.1016/j.jss.2022.06.018

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