AML
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Mutations may be a ‘missing link’ in AML
Research published in Nature Communications suggests that mutations in the ZBTB7A gene are associated with t(8;21)-rearranged acute myeloid...
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Team identifies potential therapeutic target for AML
New research suggests that E proteins and their antagonists, Id proteins, can play key roles in acute myeloid leukemia (AML). The study showed...
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Telomere length linked to neutrophil recovery in AML
Image by Volker Brinkmann Researchers say they have discovered a way to predict which children with acute myeloid leukemia (AML) are at the...
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Risk of AML death varies by region
Photo by Rhoda Baer The risk of death from acute myeloid leukemia (AML) may be influenced by where a patient lives, according to a study...
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Study: CMV doesn’t lower risk of relapse, death
Small studies have suggested that early cytomegalovirus (CMV) reactivation may protect against leukemia relapse and even death after hematopoietic...
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Study explains how a mutation spurs AML development
A set of faulty genetic instructions keeps hematopoietic stem/progenitor cells (HSPCs) from maturing and contributes to the development of acute...
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A new approach to treat AML?
Preclinical research suggests that activating the STING pathway may be a feasible approach for treating acute myeloid leukemia (AML). The STING...
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Study provides clues to AML survival after chemotherapy
Preclinical research suggests that some leukemia cells harvest energy resources from normal cells during chemotherapy, and this helps the leukemia...
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FDA reports shortage of doxorubicin for injection, initiates importation
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Acute myeloid leukemia genomic classification and prognosis
Key clinical point: Mutational analysis of 1,540 patients with acute myeloid leukemia (AML) identified 11 distinct classes with prognostic...
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Researchers identify 11 subgroups of AML
Photo courtesy of NIGMS Using patient samples from 3 prospective multicenter clinical trials of the German-Austrian AML Study Group, researchers...