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Dietary Fatty Acids Linked to Colitis Flare

Clin Gastroenterol Hepatol; 2017 Sep; Barnes, et al

Publish date:: August 31, 2017

High intake of certain dietary fatty acids may cause aminosalicylate-treated patients with ulcerative colitis (UC) to relapse, suggests a multicenter observational study that included over 400 patients at 25 locations.

Patients in the study were all in remission on monotherapy with an aminosalicylate.
Several fatty acids were linked to disease flare ups but the strongest association occurred in patients who consumed foods rich in myristic acid, which is common in palm oil, coconut oil, and dairy fats.
Foods typically associated with UC flare ups were not linked to them in this investigation, including processed meat, alcohol, and sulfur-rich foods.

Citation:

Barnes EL, Nestor M, Onyewadume L, et al. High dietary intake of specific fatty acids increases risk of flares in patients with ulcerative colitis in remission during treatment with aminosalicylates. Clin Gastroenterol Hepatol. 2017;15:1390-1396.e1. doi:10.1016/j.cgh.2016.12.036.

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