Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Esophageal and Gastric Cancer Subtypes in US
Clin Gastroenterol Hepatol; ePub 2018 Jun 11; Islami, et al
There is increasing incidence trends for esophageal adenocarcinoma (EAC), gastric cardia adenocarcinoma (GCA), and gastric non-cardia adenocarcinoma (GNCA) among several subpopulations in the US, a recent study found. Using high-quality nationwide population-based data, researchers calculated average contemporary incidence rates (2010-2014) and annual percent changes in rates (1997-2014) by race, ethnicity, and age for each cancer subtype. They found:
- From 1997 through 2014, overall esophageal squamous cell carcinoma incidence rates continuously decreased in both sexes and all racial and ethnic groups.
- Overall, EAC incidence rates decreased or stabilized during the most recent time period in men and women after increasing from 1997 through 2006 and 2007.
- However, EAC incidence rates continued to increase from 1997 through 2014 in several subpopulations, including non-Hispanic white men aged <50 years, non-Hispanic white women aged <70 years, and Asian/Pacific Islander men.
- Overall, GCA incidence rates increased among non-Hispanic whites, but decreased among Hispanics (men) and Asian/Pacific Islanders.
- Overall GNCA rates decreased in both sexes and all racial and ethnic groups; however, rates increased in young age groups among men and non-Hispanic white, non-Hispanic black, and Hispanic women.
Islami F, DeSantis CE, Jemal A. Incidence trends of esophageal and gastric cancer subtypes by race, ethnicity, and age in the United States, 1997-2014. [Published online ahead of print June 11, 2018]. Clin Gastroenterol Hepatol. doi:10.1016/j.cgh.2018.05.044.
