Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Gauging the Risk of Intraductal Pancreatic Ca
Gastroenterology; ePub 2017 Jul 21; Pergolini, et al
The risk of developing cancer among patients with branch duct intraductal papillary mucinous neoplasms (BD-IPMNs) is minimal if their cyst remains 1.5 cm or smaller for more than 5 years, according to a retrospective analysis of 577 patients evaluated at Massachusetts General Hospital. Details of the investigation include the following:
- After 5 years, malignancies occurred in 5.5% of patients.
- Invasive cancers occurred in 4.4%.
- Among the 108 patients with cysts 1.5 cm or smaller after more than 5 years of follow-up, only 1 had ductal adenocarcinoma (0.9%).
- In patients with cysts larger than 1.5 cm, 7.5% developed a malignancy.
Pergolini I, Sahora K, Ferrone CR, et al. Long-term risk of pancreatic malignancy in patients with branch duct intraductal papillary mucinous neoplasm in a referral center. [Published online ahead of print July 21, 2017]. Gastroenterology. doi:10.1053/j.gastro.2017.07.019.
This Week's Must Reads
Must Reads in Endoscopy, Pancreas, & Biliary Tract
Gender Differences in Patients Hospitalized with Cirrhosis, J Clin Gastroenterol; ePub 2019 Feb 22; Rubin, et al
POC Test for Identifying Viraemic HCV Infection, J Hepatol; ePub 2019 Feb 21; Freiman, et al
Frailty in Patients with Ascites & Hepatic Encephalopathy, Gastroenterology; ePub 2019 Jan 19; Lai, et al
Hypercholesterolemia & Statin Exposure in Cirrhosis, Gastroenterology; ePub 2019 Jan 18; Kaplan, et al
Response to UDCA Treatment in PBC Patients, Clin Gastroenterol Hepatol; ePub 2019 Jan 4; Cheung, et al