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Diarrhea Among Hospitalized Children

Vaccine; ePub 2018 Jun 1; Mulyani, et al

Rotavirus is a major cause of diarrhea in hospitalized children and inclusion of the rotavirus vaccine should be included as a treatment option, a recent study found. Children aged <5 years with acute watery diarrhea were prospectively identified and enrolled through active diarrhea surveillance system in 5 sites in 4 provinces in Indonesia during 2010-2015. Bivariate logistic regression tests were performed to compare rotavirus positive and negative results with respect to the collected demographic and clinical variables. Researchers found:

  • The average annual rotavirus prevalence among children hospitalized with acute watery diarrhea was 47.5% during the study period.
  • Rotavirus diarrhea occurred mostly in children aged <2 years.
  • Of all age groups, children aged 6-11 years and 12-23 months had the highest prevalence of rotavirus diarrhea in all years.
  • The most prevalent of G and P genotypes were G1P8 in 2010-2012 and G3P8 in 2013-2015.

Citation:

Mulyani NS, Prasetyo D, Karyana IPG, et al. Diarrhea among hospitalized children under five: A call for inclusion of rotavirus vaccine to the national immunization program in Indonesia. [Published online ahead of print June 1, 2018]. Vaccine. doi:10.1016/j.vaccine.2018.05.031.