Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Biallelic Mismatch Repair Deficiency Syndrome Guidance
Gastroenterology; ePub 2017 Mar 28; Durno, et al
The United States Multi-Society Task Force on Colorectal Cancer recently arrived at a consensus designed to help clinicians caring for patients with biallelic mismatch repair deficiency (BMMRD) syndrome, or constitutional mismatch repair deficiency syndrome. The task force statement:
- Outlines the genetic and clinical features that make BMMRD syndrome unique.
- Reviews the current management of the disorder.
- Discusses the paucity of evidence on BMMRD syndrome.
- Recognizes that despite the lack of evidence, clinicians still need advice on how to detect and manage patients with the disorder.
Durno C, Boland CR, Cohen S, et al. Recommendations on surveillance and management of biallelic mismatch repair deficiency (BMMRD) syndrome: A consensus statement by the US Multi-Society Task Force on Colorectal Cancer. [Published online ahead of print March 28, 2017]. Gastroenterology. doi:10.1053/j.gastro.2017.02.011.
This Week's Must Reads
Must Reads in Clinical Guidelines
AGA Guideline: Drug Monitoring in IBD, Gastroenterology; 2017 Sep; Feuerstein, et al
AGA Clinical Practice Update: Per-Oral Endoscopic Myotomy for Achalasia, Gastroenterology; 2017 Nov; Kahrilas, et al
AGA Clinical Practice Update: Tx for Fecal Incontinence, Clin Gastroenterol Hepatol; 2017 Dec; Bharucha, et al
ACG/CAG Updates Guidelines on Dyspepsia, Am J Gastroenterol; ePub 2017 Jun 20; Moayyedi, et al
EGFR Inhibitors Benefit Metastatic CRC Patients, Cochrane; 2017 Jun 27; Chan, et al