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Good ALL outcomes in Down syndrome children

Maloney K et al. ASPHO 2018, annual meeting of the American Society of Pediatric Hematology/Oncology Abstract PP 2001

Key clinical point: Survival rates of standard risk ALL in children with Down syndrome approach those of their peers without Down syndrome.

Major finding: The 5-year event-free survival rate for children with Down syndrome was 86% vs. 89% for children without Down syndrome (P = .025).

Study details: Follow-up of 5,311 children with newly diagnosed ALL in the COG AALL0331 trial.

Disclosures: COG AALL0331 was supported by the National Cancer Institute. Dr. Maloney reported having no financial disclosures.

Source: Maloney K et al. ASPHO 2018, Abstract PP 2001.

Citation:

Maloney K et al. ASPHO 2018, annual meeting of the American Society of Pediatric Hematology/Oncology Abstract PP 2001