Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Cochrane on Detecting CRC in Patients with IBD

Cochrane; 2017 Sep 18; Bye, Nguyen, Parker, et al

Publish date:

Colonoscopic surveillance in patients with inflammatory bowel disease (IBD) may lower the risk of developing colorectal cancer (CRC) and death associated with it, according to a Cochrane review of 5 trials involving nearly 7,200 individuals. Among the findings, based on very low-quality evidence:

  • The surveillance group had lower cancer rates; odds were reduced by 42%.
  • The surveillance group had lower rates of CRC-related death; odds were reduced by 64%.
  • The surveillance group had more early state disease detected.

Citation:

Bye W, Nguyen T, Parker C, Jairath V, East J. Strategies for detecting colon cancer in patients with inflammatory bowel disease. Cochrane Database of Syst Rev. 2017, Issue 9. Art. No.: CD000279. doi:10.1002/14651858.CD000279.pub4.

This Week's Must Reads

Must Reads in Colon and Rectal

Fiber Intake and Survival After CRC Diagnosis, JAMA Oncol; ePub 2017 Nov 2; Song, Wu, et al

Cochrane on Detecting CRC in Patients with IBD, Cochrane; 2017 Sep 18; Bye, Nguyen, Parker, et al

Statins and Survival in Patients with Cancer, JAMA Oncol; ePub 2017 Aug 22; Emilsson, et al

Cochrane on Oral vs IV Chemotherapy for CRC, Cochrane; 2017 Jul 28; Chionh, Lau, Yeung, et al

Inflammation, Sarcopenia Impact on CRC Survival , JAMA Oncol; ePub 2017 Aug 10; Cespedes Feliciano, et al