Using electromotive drug administration to administer intravesical mitomycin may delay the time to recurrence in some patients with non-muscle invasive bladder cancer, according to a Cochrane review of 3 studies involving 672 individuals. The impact of serious adverse events is not certain, however. Among the findings:

• It is not known whether using an electrical current to give a course of mitomycin after endoscopic surgery is better or worse than Bacillus Calmette-Guérin (BCG) or mitomycin without electrical current.
• Mitomycin with electrical current and BCG given over a longer time period may delay tumor recurrence and spread better than BCG alone.
• Giving 1 dose of mitomycin with electrical current before endoscopic surgery may be work better than doing the same without electric current after surgery.
• It also may work better than surgery alone without further treatment.