Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Glucose Self-Monitoring in Non-Insulin Treated Patients with T2D
JAMA Intern Med; ePub 2017 Jun 10; Young, et al
For most patients with non-insulin-treated type 2 diabetes, routine self-monitoring of blood glucose levels does not significantly improve hemoglobin A1c levels or health-related quality of life (HRQOL), a recent study found. The Monitor Trial study was conducted in 15 primary care practices in North Carolina between January 2014 and July 2015. Eligible patients (aged <30 years) with type 2 non-insulin-treated diabetes were established with a PCP at a participating practice and had glycemic control levels >6.5% but lower than 9.5% within the 6 months preceding screening. Patients were randomized to 1 of 3 groups: no self-monitoring of blood glucose (SMBG), once-daily SMBG, and once-daily SMBG with enhanced patient feedback. Researchers found:
- 450 patients were randomized; 418 (93%) completed the final visit.
- There were no clinically or statistically significant differences at 1 year in glycemic control or HRQOL between patients who performed SMBG vs those who did not.
- The addition of tailored feedback through messaging via a meter did not provide any advantage in glycemic control.
Young LA, Buse JB, Weaver MA, et al. Glucose self-monitoring in non–insulin-treated patients with type 2 diabetes in primary care settings. A randomized trial. [Published online ahead of print June 10, 2017]. JAMA Intern Med. doi:10.1001/jamainternmed.2017.1233.
It seems intuitively obvious that self-monitoring of blood glucose in patients on oral agents for type 2 diabetes would improve their glucose control. Unfortunately, that which is obvious is not always correct, and this study, along with a number of previous studies, does not support the contention that self-monitoring for patients on oral agents with type 2 diabetes improved diabetes control.1,2 What clinical practice conclusions should we draw from this study? First, the evidence suggests that self-monitoring of blood glucose is not a necessary part of care for all patients with type 2 diabetes. Second, self-monitoring of blood glucose may still have efficacy for select patients who are highly motivated and would find feedback of self-monitoring useful, as well as for patients who are at elevated risk for hypoglycemia. —Neil Skolnik, MD