Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Role of cadmium from tobacco smoke in smoking-induced osteoporosis

Publish date:: May 4, 2020

Key clinical point: Cadmium from tobacco smoke may play a key causative role in smoking-induced osteoporosis.

Major finding: Significant inverse associations were observed between smoking and total body, total hip, and trochanter bone mineral density (BMD). The indirect effects of cadmium accounted for 43% of the total effects of smoking for whole body BMD and even higher for total hip and trochanter BMD.

Study details: The study analyzed 886 elderly men from the Swedish cohort of the Osteoporotic Fractures in Men (MrOS) study.

Disclosures: This study was supported by the Swedish government, the Swedish county councils, the Swedish Research Council, and the Swedish Research Council for Health, Working Life, and Welfare. The authors declared no conflict of interest.

Citation:

Li H et al. J Bone Miner Res. 2020 Mar 19. doi: 10.1002/jbmr.4014.

This Week's Must Reads

Higher dose maximizes effects of magnesium sulfate for obese women,

Microplastics permeate human placentas,

One in five gestational carriers do not meet ASRM criteria,

Gender surgical outcomes differ following puberty suppression,

COVID-19 vaccine found effective but doctors watching for reactions, adverse events,

Must Reads in Osteoporosis

Risk factors for osteoporosis in CHF patients,

Switching to denosumab prevents osteoporosis progression in postmenopausal women with T2D,

Higher prevalence of periapical lesions in patients with osteoporosis,

Psoriasis tied to increased risk for osteoporosis,

BMD and bone turnover after gastric bypass vs. sleeve gastrectomy,