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RYGB Mortality Benefit Higher in These Patients

Diabetes Care; ePub 2017 Jul 31; Lent, et al

The mortality benefits of Roux-en-Y gastric bypass (RYGB) appear to occur mostly in patients who have diabetes at the time of surgery, according to a study involving nearly 5,700 individuals.

Participants included people who had RYGB (n=3,242) and matched controls who didn’t (n=2,428). Investigators looked at mortality differences in patients in each group with and without diabetes. Among the results:

  • All-cause mortality odds were 56% lower in patients with diabetes who underwent RYGB, compared with their counterparts who did not have surgery.
  • Mortality was not significantly different in patients without diabetes in each group.
  • Deaths rates from cardiovascular diseases, respiratory conditions, and diabetes were higher in with diabetes than they were in patients with diabetes who had surgery.
  • Patients without diabetes who underwent RYGB were less likely to die of cancer and respiratory diseases than their counterparts in the control group.

Citation:

Lent M, Benotti P, Mirshahi T, et al. All-cause and specific-cause mortality risk after Roux-en-Y gastric bypass in patients with and without diabetes. [Published online ahead of print July 31, 2017]. Diabetes Care. doi:10.2337/dc17-0519.