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Cutaneous T-Cell Lymphoma Risk Factors Examined
Int J Dermatol; ePub 2017 Jul 7; Chang, Weaver, et al
The risk of cutaneous T-cell lymphoma (CTCL) is greater in men with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL) than in the general population, according to a recent study. In addition, in patients with non-Hodgkin lymphoma (NHL), both men and women, are at greater risk for CTCL than in the general population. Researchers searched the SEER 13 registries for patients with a diagnosis of CLL and NHL between 1992 and 2008. Among patients identified, they evaluated the incidence of CTCL, and found:
- Among 31,286 patients with CLL, the incidence of CTCL was not significantly higher in men than women: 104.2 and 28.1 per 1,000,000 person-years, respectively.
- Among 97,691 patients with NHL, the incidence of CTCL was similar in men and women (97.9 and 92.0 per 1,000,000 person-years, respectively).
- The incidence of CTCL among males with CLL, males with NHL, and females with NHL was significantly higher than expected in the general population.
Chang TW, Weaver AL, Shanafelt TD, et al. Risk of cutaneous T-cell lymphoma in patients with chronic lymphocytic leukemia and other subtypes of non-Hodgkin lymphoma. [Published online ahead of print July 7, 2017]. Int J Dermatol. doi:10.1111/ijd.13653.