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Aspirin May Aid Survival in Melanoma
J Am Acad Dermatol; ePub 2018 Jan 6; Rachidi, et al
Aspirin could provide a survival advantage in melanoma, according to a recent study. Researchers evaluated data from a retrospective cohort of 1,522 patients at Indiana University Health (IUH) diagnosed with melanoma between 2000 and 2014 and followed up through September, 2016. They found:
- Aspirin use was associated with longer overall survival in univariate analysis and after controlling for age, sex, stage, and treatment modalities.
- Aspirin use was not associated with survival in patients with in situ and stage I melanoma, but was associated with better survival in stages II and III.
- No statistical significance was observed in stage IV patients.
- In turn, patients using aspirin before diagnosis were less likely to be diagnosed in stages III or IV disease.
Citation:
Rachidi S, Wallace K, Li H, Lautenschlaeger T, Li Z. Post-diagnosis aspirin use and overall survival in patients with melanoma. [Published online ahead of print January 6, 2018]. J Am Acad Dermatol. doi:10.1016/j.jaad.2017.12.076.