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Ambient UVI Associated with Melanoma in Males

J Am Acad Dermatol; ePub 2016 Oct 26; Liu-Smith, et al

Publish date:

Ambient ultraviolet index (UVI) appears to be associated with melanoma incidence in males but not in females, a recent study found. Researchers collected cutaneous melanoma (CM) data and daily UVI from 31 cancer registries for association analysis. A second dataset from 42 US states was used for validation. They found:

  • There was no association between log-transformed female CM rates and levels of UVI, but there was a significant association between male rates and UVI and a significant association between overall rates and UVI.
  • The 5-year age-specific rate–UVI association levels increased with age in men, but age-specific levels remained low and unchanged in women.
  • The significant rate–UVI association in men, and nonassociation in women, was validated in a population of white residents of the US.

Citation:

Liu-Smith F, Farhat AM, Arce A, et al. Sex differences in the association of cutaneous melanoma incidence rates and geographic ultraviolet light exposure. [Published online ahead of print October 26, 2016]. J Am Acad Dermatol. doi:10.1016/j.jaad.2016.08.027.

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