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Childhood BMI tied to hidradenitis suppurativa in adulthood
Key clinical point: Childhood body mass index (BMI) is positively associated with the risk of developing hidradenitis suppurativa (HS) in adulthood.
Major finding: Both the lightest (2.00-2.75 kg; hazard ratio [HR], 1.36; 95% confidence interval [CI], 1.10-1.68) and the heaviest babies at birth (4.26-5.50 kg; HR, 1.39; 95% CI, 1.01-1.93) had an increased risk of developing HS vs. normal-weight babies (3.26-3.75 kg). Children with overweight at 7 years of age but with normal weight at 13 years of age reduced the risk of HS development in adulthood (HR, 1.05; 95% CI, 0.67-1.67).
Study details: The data come from a cohort study of 347,200 Danish children born between 1930 and 1996; the follow-up period was from 1977 to 2017.
Disclosures: This study is supported in part by a grant from the Novo Nordisk Foundation. The authors declared no conflicts of interest.
Jørgensen AHR et al. JAMA Dermatol. 2020 Apr 29. doi: 10.1001/jamadermatol.2020.1047.