Cyanoacrylate tissue adhesives produce cosmetic outcomes that are not statistically significantly different than sutures, according to a recent study. Furthermore, they are associated with fast application, easy wound care, and patient satisfaction. 71 patients scheduled for skin cancer excision were included in this prospective, randomized, single-blind study. Cosmetic appearance was assessed by a masked panel of dermatologists and plastic surgeons who evaluated digital photographs. Secondary outcomes were assessed by nursing recordings and patient and surgeon evaluations. They found:

• There was no significant difference in wound appearance (Visual Analog Scale: p=.4693, modified Hollander Wound Evaluation Score: p=.6413) between adhesives and sutures.
• It was faster and easier for a surgeon to use adhesives, and subjects spent less time caring for and were more satisfied by wounds sealed with adhesives than sutures.