Clinical Edge Journal Scan

Atopic dermatitis is associated with increased prevalence of inflammatory bowel disease


 

Key clinical point: Patients with atopic dermatitis (AD), especially moderate-to-severe AD, had an increased prevalence of inflammatory bowel disease (IBD).

Major finding: A significant association was observed between IBD and AD (adjusted odds ratio [aOR] 3.89; P = .0169); however, when stratified by AD severity, only moderate-to-severe AD was found to be associated with IBD (aOR 4.45; P = .0102).

Study details: Findings are from a retrospective observational study including 364 patients with AD and 725 matched control individuals without AD.

Disclosures: This study was sponsored by an independent investigator grant from AbbVie. Two authors declared serving as investigators for or receiving honoraria or fees as consultants or advisory board members from various organizations, including AbbVie. The other authors declared no conflicts of interest.

Source: Rom H et al. The association between atopic dermatitis and inflammatory bowel disease in adults: A cross-sectional study in a specialized atopic dermatitis clinic. J Eur Acad Dermatol Venereol. 2023 (Dec 21). doi: 10.1111/jdv.19769

Recommended Reading

AAAAI/ACAAI Joint Task Force Issues Updated ‘Practice-Changing’ Guidelines to Manage AD
MDedge Dermatology
Atopic dermatitis not linked with increased venous thromboembolism risk
MDedge Dermatology
Atopic dermatitis not linked with increased venous thromboembolism risk
MDedge Dermatology
Interim analysis confirms the safety and efficacy of dupilumab in atopic dermatitis
MDedge Dermatology
Rademikibart shows promise in moderate-to-severe atopic dermatitis
MDedge Dermatology
Aggregate response benefit in skin clearance and itch reduction favor upadacitinib over dupilumab in AD
MDedge Dermatology
Allergic contact dermatitis a crucial comorbidity in atopic dermatitis
MDedge Dermatology
Rapid and sustained improvement in skin pain with abrocitinib in atopic dermatitis
MDedge Dermatology
Abrocitinib downregulates genes associated with atopic dermatitis pathology
MDedge Dermatology
Real-world study confirms the multidimensional efficacy of tralokinumab in atopic dermatitis
MDedge Dermatology