Clinical Edge Journal Scan

Atopic dermatitis: Face masks may be protective on facial eczema and may enhance dupilumab efficacy


 

Key clinical point: Face masks worn during the COVID-19 pandemic increased the quality of life by covering facial eczemas and increased the efficacy of dupilumab therapy by minimizing exposure to allergens and air pollution in patients with atopic dermatitis (AD).

Major finding: Although the prevalence of facial eczema was similar before and after the COVID-19 pandemic ( P = .7618), patients with AD showed improved Dermatology Life Quality Index scores at baseline (13.14 vs. 23.06; P < .0001) along with a higher reduction in Eczema Area and Severity Index scores after 16 weeks of dupilumab treatment (−21.46 vs. −17.83; P = .0001) in the post- vs. pre-pandemic period.

Study details: Findings are from a retrospective study including 64 adults with moderate-to-severe AD who were assessed for facial involvement at baseline and after 16 weeks of dupilumab therapy in both the pre- and post-pandemic periods.

Disclosures: This study did not receive any funding. The authors declared no conflicts of interest.

Source: Vanessa M et al. Facial dermatoses and use of protective mask during Covid-19 pandemic: A clinical and psychological evaluation in patients affected by moderate–severe atopic dermatitis under treatment with dupilumab. Dermatol Ther. 2022; e15573 (May 10). Doi: 10.1111/dth.15573

Recommended Reading

Commentary: Comparisons of Dupilumab and Other Atopic Dermatitis Treatments, June 2022
MDedge Dermatology
FDA approves dupilumab for children with eczema aged 6 months to 5 years
MDedge Dermatology
Therapeutic patient education can help with adherence to treatment
MDedge Dermatology
Atopic dermatitis: Options abound, and more are coming
MDedge Dermatology
Long-term safety and efficacy of dupilumab in adolescents with moderate-to-severe atopic dermatitis
MDedge Dermatology
Moderate-to-severe atopic dermatitis: Rapid improvement in itch with baricitinib vs. dupilumab
MDedge Dermatology
Fluctuating and persistent depressive symptoms in patients with atopic dermatitis
MDedge Dermatology
Dupilumab effective in adults with moderate-to-severe atopic dermatitis in real world
MDedge Dermatology
Meta-analysis shows protective effect of probiotics on infantile atopic dermatitis
MDedge Dermatology
Probiotic supplementation beneficial in adults with atopic dermatitis
MDedge Dermatology