Key clinical point: In children with atopic dermatitis (AD), skin pain is a burdensome symptom with heterogeneous presentation and is associated with decreased quality of life (QoL).
Major finding: Skin pain intensity was associated with conditions such as bleeding (adjusted β 1.47; 95% CI 0.61-2.33), weeping/oozing (adjusted β 1.18; 95% CI 0.47-1.90), and cracking of skin (adjusted β 1.00; 95% CI 0.27-1.73). Parent-reported pain intensity was associated with impaired QoL in infants aged 1-4 years (adjusted β 1.16; 95% CI 0.18-2.14) and children aged 5-17 years (adjusted β 1.68; 95% CI 1.00-2.36).
Study details: Findings are from a cross-sectional national survey of 240 children with AD and their parents, of which 60 and 180 were aged 1-4 years and 5-17 years, respectively, and 200 had moderate-to-very severe disease.
Disclosures: This study was funded by the Agency for Healthcare Research and Quality. The authors declared no conflicts of interest.
Source: Cheng BT et al. J Allergy Clin Immunol Pract. 2021 (Dec 23) . Doi: 10.1016/j.jaip.2021.12.012.