Fast Facts for Board Review

Genetic Pathways, Part 1

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5. A young child presents with linear atrophic plaques with fat herniation and raspberrylike oral papillomas. What signal transduction pathway is altered in this syndrome?

a. ABCA12 (ATP-binding cassette, sub-family A, member 12)

b. adenylate cyclase

c. ß-catenin

d. LEKTI (lympho-epithelial Kazal-type-related inhibitor)

e. nuclear factor κ light chain enhancer of activated B cells


The answers appear on the next page.

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