Fast Facts for Board Review

Genetic Pathways, Part 1

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3. A 30-year-old man presented for evaluation of abnormal nails. Physical examination revealed a red streak with distal V-shaped nicking. Numerous keratotic papules on the hands and chest and oral papules also were noted. The gene responsible for these findings encodes a Ca2+-ATPase responsible for a Ca2+ influx into what cellular structure?

a. cytoplasm

b. endoplasmic reticulum

c. golgi

d. nucleus

e. ribosome

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