Applied Evidence
-
Applied Evidence
PPI therapy: When to worry about fracture risk
High-dose, long-term use of proton pump inhibitors may increase fracture risk, but the evidence is inconclusive. Here’s what to keep in mind.
-
Applied Evidence
It's time to abandon the sliding scale
-
Applied Evidence
Rotavirus infection: Optimal treatment and prevention
Which fluids should you avoid when treating patients’ gastroenteritis? Should nursing mothers continue to breastfeed? And what about the timing of...
Clinical Inquiries
-
Clinical Inquiries
What are the adverse effects of prolonged opioid use in patients with chronic pain?
EVIDENCE-BASED ANSWER: CONSTIPATION, NAUSEA, AND DYSPEPSIA are the most common long-term adverse effects of chronic opioid use (strength of...
-
Clinical Inquiries
Which oral antibiotics are best for acne?
EVIDENCE-BASED ANSWER: DOXYCYCLINE IS EFFECTIVE (strength of recommendation [SOR]: B, randomized controlled trial) and the antibiotic of choice (...
-
Clinical Inquiries
Which treatments provide the most relief for pharyngitis pain?
EVIDENCE-BASED ANSWER: NONSTEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs), acetaminophen, antibiotics, and oral and intramuscular steroids are...
-
Clinical Inquiries
When is the best time to clamp the umbilical cord after routine vaginal delivery?
EVIDENCE-BASED ANSWER: SOMETIME BETWEEN 30 SECONDS AND 2 MINUTES after delivery appears to be the best interval. In term infants, delayed clamping...
-
Clinical Inquiries
How effective—and safe—are systemic steroids for acute low back pain?
EVIDENCE-BASED ANSWER: SHORT COURSES OF SYSTEMIC STEROIDS ARE LIKELY SAFE, but they are ineffective. A single dose of intramuscular (IM) or...
Commentary
Case Reports
-
Case Reports
Recent onset of confusion, limited mobility, and disturbed sleep-wake cycle
This elderly woman had received treatment the week before for pneumonia and paranoid behavior. How would you proceed with her care?
Photo Rounds
-
Photo Rounds
Returning traveler with painful penile mass
Our patient thought he’d practiced “safe sex” while traveling in Vietnam. But a week after his return, he sought care for a tender penile lump and...
-
Photo Rounds
Diffuse rash, muscle weakness
-
Photo Rounds
Rash on face
-
Photo Rounds
Patches of tough skin
-
Photo Rounds
Red spots on face
Practice Alert
-
Practice Alert
ACIP immunization update
ACIP’s recommendations stress the need to protect vulnerable populations from rising rates of pertussis infection, improve health care personnel...
Medical Verdicts
PURLs
-
PURLs
Is your patient still using rosiglitazone?
Many doctors stopped prescribing rosiglitazone in 2007, when a study linked it to an elevated MI risk. An update to that study underscores the...
CME Supplements
-
Sponsored Supplement
Primary Care Management of Patients With Asthma