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Adult Immunization Schedule for 2016

ACIP offers practice recommendations for adults

The Advisory Committee on Immunization Practices (ACIP) has approved the recommended immunization schedule for adults 19 years or older in the US. Changes in the 2016 adult immunization schedule from the 2015 schedule include the following new ACIP recommendations:

• Interval change for 13-valent pneumococcal conjugate vaccine (PCV13) followed by 23-valent pneumococcal polysaccharide vaccine (PPSV23) was changed from 6 to 12 months to at least 1 year for adults aged ≥65 years who do not have immunocompromising conditions, anatomical or functional asplenia, cerebrospinal fluid leaks, or cochlear implants. The interval for adults aged ≥19 years with any of these conditions is at least 8 weeks.

• Serogroup B meningococcal (MenB) vaccine series should be administered to certain groups of persons aged ≥10 years who are at increased risk for serogroup B meningococcal disease.

• MenB vaccine series may be administered to adolescents and young adults aged 16 through 23 years (preferred age is 16 through 18 years) to provide short-term protection against most strains of serogroup B meningococcal disease.

• Nine-valent human papillomavirus (HPV) vaccine (9vHPV) has been added to the schedule and can be used for routine vaccination of females and males against HPV.

Citation: Kim DK, Bridges CB, Harriman KH. Advisory Committee on Immunization Practices recommended immunization schedule for adults aged 19 years or older — United States, 2016. MMWR Morb Mortal Wkly Rep 2016;65:1-3. doi: http://dx.doi.org/10.15585/mmwr.mm6504a5er.

Commentary: Each January the ACIP issues revised immunization recommendations for children and adults. The pneumococcal vaccine recommendations have been clarified and made easier to follow as PCV13 is given first at age 65, and then 1 year later PPSV23 is given. The largest change this year is the addition of MenB vaccine. MenB vaccine is recommended for routine use in persons aged >10 years who are at increased risk for serogroup B meningococcal disease. The incidence of serogroup B meningococcal disease is stable and low with the majority (>80%) of cases occurring in older adolescents and young adults aged 16 to 23 years. The preferred age for MenB vaccination is 16 to 18 years. MenB vaccine is available as a 2-dose series of MenB-4C vaccine (Bexsero) administered at least 1 month apart or a 3-dose series of MenB-FHbp (Trumenba) vaccine administered at 0, 2, and 6 months; the 2 MenB vaccines are not interchangeable, i.e., the same MenB vaccine product must be used for all doses. —Neil Skolnik, MD