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Study supports banning probiotics from the ICU
The risk is particularly acute for powdered formulations, presumably because powder more easily disseminates to contaminate central venous...
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Sham-controlled renal denervation trial for hypertension is a near miss
The SPYRAL HTN–ON MED trial missed its primary endpoint, likely caused in part by imbalances in medication use.
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First-line AFib ablation cuts risk of progression vs. drug therapy
Atrial fibrillation treated with ablation rather than drug therapy was less likely to progress to persistent symptoms in the PROGRESSIVE-AF trial...
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If a saphenous graft is available, treat limb threatening ischemia surgically
Surgery beats endovascular treatment for limb threatening ischemia when saphenous grafts are an option, according to the BEST-CLI trial.
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Precision CAD testing shows 70% cut in composite risk at 1 year
A streamlined protocol for evaluating suspected stable chest pain substantially improved outcomes at 1 year in the PRECISE trial.
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In CABG, radial artery works best for second key graft: RAPCO at 15 years
With more than 15 years of follow-up, the radial artery beats other options for the second key coronary target in coronary artery bypass surgery...
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Triglyceride-lowering fails to show CV benefit in large fibrate trial
In the phase 3 PROMINENT trial, pemafibrate improved multiple lipid fractions in patients with type 2 diabetes, without any impact on...
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Pulmonologist consult at COPD admission reduces risk of return
“When stratified by severity of COPD at the time of admission, the difference in the readmission rate was even greater.”
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Testosterone ranges for young men could help classify deficiency
For young men complaining of hypogonadal symptoms, new reference testosterone ranges may have clinical use, but experts have their doubts.
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Two-year dupilumab data: Continued response for moderate to severe pediatric asthma
“I think it is really important that children with asthma finish their childhood with the best bone health and the lowest risk of other steroid-...
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Pregnancy termination counseling for lung disease requires new caution
“If the advice is interpreted as aiding and abetting an elective abortion, it is a felony offense in some states.”
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Large trial of home-based COPD rehab shows positive results
Those assigned to the intervention had a significant and clinically meaningful improvement.
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SPRINT’s intensive therapy benefit fades once BP creeps back up
Despite an all-cause mortality benefit from intensive therapy in SPRINT, benefit was lost after the trial.
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Monkeypox features include mucocutaneous involvement in almost all cases
In Europe, the data support monkeypox as a largely sexually transmitted disease that self-resolves in about 4 weeks.
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Post-PCI FFR in multivessel disease predicts target vessel failure: FAME 3 analysis
Fractional flow reserve measurements in three-vessel PCI interventions predicts vessel and patient outcomes.