News
Eight-week, three-drug regimen produces SVR over 90% in HCV
A triple antiviral combination with direct-acting antiviral agents was associated with high rates of sustained virologic response across all three...
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Pan-caspase inhibitor controls cirrhosis-associated portal hypertension
Emricasan, a caspase inhibitor, achieves a significant reduction in portal pressure among patients with cirrhosis and severe portal hypertension,...
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Lusutrombopag is effective for thrombocytopenia in liver disease
Key clinical point: In a phase III trial, lusutrombopag was found to reduce the need for platelet transfusion in chronic liver disease patients...
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AHA: Mixed results for mitral valve replacement vs. repair
Mitral valve replacement reduced regurgitation better than valve repair, but it didn’t significantly improve left ventricular function or survival...
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New targeted Crohn’s therapy performs well in phase III trial
Ustekinumab, a monoclonal antibody targeted against interleukins 12 and 23 (IL-12 and IL-23), met its primary endpoint for control of Crohn’s...
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Early TIPS tied to mortality reduction in esophageal bleeds
Early use of a transjugular intrahepatic portosystemic shunt is associated with substantial reductions in mortality.
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Disparity found in PPI risk perception among physicians
A survey of almost 500 physicians found that primary care physicians (PCPs) are far more concerned about the reported adverse effects of proton...
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DNA-based pancreatic cyst test guides treatment
A DNA-based molecular diagnostic test that stratifies pancreatic cysts for their malignant potential better than current alternatives can help...
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GI bleeds in obese patients more complicated but no more fatal
Obese patients who develop an upper GI bleed receive more treatment, are more likely to develop hemorrhagic shock, and are more likely to require...
